منابع مشابه
Fat(al) attraction: oxidized lipids act as "eat-me" signals.
Phagocytosis of apoptotic cell corpses is a conserved and well-regulated process and is required to maintain tissue homeostasis within an organism. Evidence suggests that apoptotic cell engulfment by macrophages is dependent upon the externalization of phosphatidylserine (PS) on the plasma membrane of the dying cell. Furthermore, oxidation of PS and other phospholipids may serve to facilitate c...
متن کاملPyroptotic cells externalize eat-me and release find-me signals and are efficiently engulfed by macrophages.
Pathogenic intracellular bacteria often hijack macrophages for their propagation. The infected macrophages release IL-1β and IL-18 and simultaneously commit suicide, which is called pyroptosis; both responses require caspase-1. Here, we found that pyroptotic cells induced by microbial infection were efficiently engulfed by human monocytic THP-1-cell-derived macrophages or mouse peritoneal macro...
متن کاملFind-me and eat-me signals in apoptotic cell clearance: progress and conundrums
Everyday we turnover billions of cells. The quick, efficient, and immunologically silent disposal of the dying cells requires a coordinated orchestration of multiple steps, through which phagocytes selectively recognize and engulf apoptotic cells. Recent studies have suggested an important role for soluble mediators released by apoptotic cells that attract phagocytes ("find-me" signals). New in...
متن کامل'Like me, want me, buy me, eat me': relationship-building marketing communications in children's magazines.
OBJECTIVE Television, Internet and print media are saturated with advertisements for unhealthy food that use marketing tactics aimed to build long-term brand loyalty and 'relationships' with children. While research in this area has largely focused on television, the current study examines children's responses to relationship-building marketing communications found in popular children's magazin...
متن کامل2010 ' Like me , want me , buy me , eat me ' : relationship - building marketing communications in children ' s magazines
Objective: Television, Internet and print media are saturated with advertisements for unhealthy food that use marketing tactics aimed to build long-term brand loyalty and ‘relationships’ with children. While research in this area has largely focused on television, the current study examines children’s responses to relationshipbuilding marketing communications found in popular children’s magazin...
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ژورنال
عنوان ژورنال: Nature Reviews Immunology
سال: 2007
ISSN: 1474-1733,1474-1741
DOI: 10.1038/nri2222